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polyclonal neutralizing antibody against tlr4  (R&D Systems)


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    R&D Systems polyclonal neutralizing antibody against tlr4
    Figure 4. HMGB1-induced release of IL-6 and TNF via <t>TLR4</t> is not inhibited by HBP08. The concentration of IL-6 (A) and TNF (B) in the supernatant of monocytes treated with HMGB1 in the presence of HBP08 or a <t>neutralizing</t> antibody against TLR4 (αTLR4) was measured by CBA. Data are shown as the mean ± SEM of at least four independent experiments performed. ***p < 0.001; ****p < 0.0001 by one-way ANOVA, followed by Dunnett’s multicomparison test.
    Polyclonal Neutralizing Antibody Against Tlr4, supplied by R&D Systems, used in various techniques. Bioz Stars score: 99/100, based on 59 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/polyclonal neutralizing antibody against tlr4/product/R&D Systems
    Average 99 stars, based on 59 article reviews
    polyclonal neutralizing antibody against tlr4 - by Bioz Stars, 2026-03
    99/100 stars

    Images

    1) Product Images from "Systematic Development of Peptide Inhibitors Targeting the CXCL12/HMGB1 Interaction."

    Article Title: Systematic Development of Peptide Inhibitors Targeting the CXCL12/HMGB1 Interaction.

    Journal: Journal of medicinal chemistry

    doi: 10.1021/acs.jmedchem.1c00852

    Figure 4. HMGB1-induced release of IL-6 and TNF via TLR4 is not inhibited by HBP08. The concentration of IL-6 (A) and TNF (B) in the supernatant of monocytes treated with HMGB1 in the presence of HBP08 or a neutralizing antibody against TLR4 (αTLR4) was measured by CBA. Data are shown as the mean ± SEM of at least four independent experiments performed. ***p < 0.001; ****p < 0.0001 by one-way ANOVA, followed by Dunnett’s multicomparison test.
    Figure Legend Snippet: Figure 4. HMGB1-induced release of IL-6 and TNF via TLR4 is not inhibited by HBP08. The concentration of IL-6 (A) and TNF (B) in the supernatant of monocytes treated with HMGB1 in the presence of HBP08 or a neutralizing antibody against TLR4 (αTLR4) was measured by CBA. Data are shown as the mean ± SEM of at least four independent experiments performed. ***p < 0.001; ****p < 0.0001 by one-way ANOVA, followed by Dunnett’s multicomparison test.

    Techniques Used: Concentration Assay



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    R&D Systems polyclonal neutralizing antibody against tlr4
    Figure 4. HMGB1-induced release of IL-6 and TNF via <t>TLR4</t> is not inhibited by HBP08. The concentration of IL-6 (A) and TNF (B) in the supernatant of monocytes treated with HMGB1 in the presence of HBP08 or a <t>neutralizing</t> antibody against TLR4 (αTLR4) was measured by CBA. Data are shown as the mean ± SEM of at least four independent experiments performed. ***p < 0.001; ****p < 0.0001 by one-way ANOVA, followed by Dunnett’s multicomparison test.
    Polyclonal Neutralizing Antibody Against Tlr4, supplied by R&D Systems, used in various techniques. Bioz Stars score: 99/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/polyclonal neutralizing antibody against tlr4/product/R&D Systems
    Average 99 stars, based on 1 article reviews
    polyclonal neutralizing antibody against tlr4 - by Bioz Stars, 2026-03
    99/100 stars
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    Figure 4. HMGB1-induced release of IL-6 and TNF via TLR4 is not inhibited by HBP08. The concentration of IL-6 (A) and TNF (B) in the supernatant of monocytes treated with HMGB1 in the presence of HBP08 or a neutralizing antibody against TLR4 (αTLR4) was measured by CBA. Data are shown as the mean ± SEM of at least four independent experiments performed. ***p < 0.001; ****p < 0.0001 by one-way ANOVA, followed by Dunnett’s multicomparison test.

    Journal: Journal of medicinal chemistry

    Article Title: Systematic Development of Peptide Inhibitors Targeting the CXCL12/HMGB1 Interaction.

    doi: 10.1021/acs.jmedchem.1c00852

    Figure Lengend Snippet: Figure 4. HMGB1-induced release of IL-6 and TNF via TLR4 is not inhibited by HBP08. The concentration of IL-6 (A) and TNF (B) in the supernatant of monocytes treated with HMGB1 in the presence of HBP08 or a neutralizing antibody against TLR4 (αTLR4) was measured by CBA. Data are shown as the mean ± SEM of at least four independent experiments performed. ***p < 0.001; ****p < 0.0001 by one-way ANOVA, followed by Dunnett’s multicomparison test.

    Article Snippet: A polyclonal neutralizing antibody against TLR4 (AF1478, R&D System) was used to block TLR4 engagement.

    Techniques: Concentration Assay